What Is Biotechnology And Its Ramification To Breast Cancer

Biotechnology and its Ramification to Breast Cancer According to the Centers of Disease Control and Prevention (CDC) in 2014; 236,968 women and 2,141 men in the United States were diagnosed with breast cancer. And 41,211 women and 465 men in the United States died from breast cancer (U.S. Cancer Statistics Working Group, 2017). That volume of death could have drastically been decreased if the clinicians, physicians, and oncologists utilized the Mammaprint. To understand the way Mammaprint makes a difference we first need to understand breast cancer at different levels. Some ideas we need to know are about the way that breast cancer evolves and utilizes energy, the different biomarkers and genetic makeup of breast cancer, chemotherapeutics†¦show more content†¦Warburg), the standard process in cancer metabolism (Gentric, 2017). We need to consider the significant role of TME, especially CAFs and immune cells, which profoundly participate in the metabolic interplay with neoplastic cells. CAFs and immune cells can collectively adapt to the metabolic needs of cancer cells and thus participate in tumorigenesis. Metabolic balance between all these players also promotes resistance to treatments, including not only the conventional chemotherapy or radiotherapy but also the most recent and advanced immunotherapies. Characterizing the mutual metabolic interplay between stromal, immune, and neoplastic cells will likely provide a better understanding of tumor progression and treatment resistance (Gentric, 2017). Biomarkers and Genetic Polymorphism Genome studies have identified about 80 or more genetic variants or single nucleotide polymorphisms (SNPs) linked with breast cancer risk. Each variant only discreetly alters breast cancer risk; however, together they add large risk data to current risk analysts. Therefore, when added to traditional risk models, such as the Gail model, the Tyrer-Cuzick model and/or the Breast Cancer Surveillance Consortium (BSCC) model, a combination of genetic risk factors can be used to increase risk arrangement. Risk arrangements with SNPs and other genetic alternates may also be useful to aid in other decisions for breast cancer prevention and screening. ForShow MoreRelatedDeveloping Management Skills404131 Words   |  1617 Pagessolution for courses in Principles of Management, Human Resources, Strategy, and Organizational Behavior that helps you actively study and prepare material for class. Chapter-by-chapter activities, including built-in pretests and posttests, focus on what you need to le arn and to review in order to succeed. Visit www.mymanagementlab.com to learn more. DEVELOPING MANAGEMENT SKILLS EIGHTH EDITION David A. Whetten BRIGHAM YOUNG UNIVERSITY Kim S. Cameron UNIVERSITY OF MICHIGAN PrenticeRead MoreManagement Course: Mba−10 General Management215330 Words   |  862 Pageseconomic, social, and political churning, how will these driving factors be influenced by the brutally competitive global economy in which organizations do not have any particular geographic identity or travel under any particular national passport? What will be the effect of the rapid gyrations in markets that emphasize the difficulties that accounting practices face in determining true performance costs and that forecasting programs confront in establishing the economic determinants of corporate