Thursday, May 21, 2020

What Is Biotechnology And Its Ramification To Breast Cancer

Biotechnology and its Ramification to Breast Cancer According to the Centers of Disease Control and Prevention (CDC) in 2014; 236,968 women and 2,141 men in the United States were diagnosed with breast cancer. And 41,211 women and 465 men in the United States died from breast cancer (U.S. Cancer Statistics Working Group, 2017). That volume of death could have drastically been decreased if the clinicians, physicians, and oncologists utilized the Mammaprint. To understand the way Mammaprint makes a difference we first need to understand breast cancer at different levels. Some ideas we need to know are about the way that breast cancer evolves and utilizes energy, the different biomarkers and genetic makeup of breast cancer, chemotherapeutics†¦show more content†¦Warburg), the standard process in cancer metabolism (Gentric, 2017). We need to consider the significant role of TME, especially CAFs and immune cells, which profoundly participate in the metabolic interplay with neoplastic cells. CAFs and immune cells can collectively adapt to the metabolic needs of cancer cells and thus participate in tumorigenesis. Metabolic balance between all these players also promotes resistance to treatments, including not only the conventional chemotherapy or radiotherapy but also the most recent and advanced immunotherapies. Characterizing the mutual metabolic interplay between stromal, immune, and neoplastic cells will likely provide a better understanding of tumor progression and treatment resistance (Gentric, 2017). Biomarkers and Genetic Polymorphism Genome studies have identified about 80 or more genetic variants or single nucleotide polymorphisms (SNPs) linked with breast cancer risk. Each variant only discreetly alters breast cancer risk; however, together they add large risk data to current risk analysts. Therefore, when added to traditional risk models, such as the Gail model, the Tyrer-Cuzick model and/or the Breast Cancer Surveillance Consortium (BSCC) model, a combination of genetic risk factors can be used to increase risk arrangement. Risk arrangements with SNPs and other genetic alternates may also be useful to aid in other decisions for breast cancer prevention and screening. ForShow MoreRelatedDeveloping Management Skills404131 Words   |  1617 Pagessolution for courses in Principles of Management, Human Resources, Strategy, and Organizational Behavior that helps you actively study and prepare material for class. Chapter-by-chapter activities, including built-in pretests and posttests, focus on what you need to le arn and to review in order to succeed. Visit www.mymanagementlab.com to learn more. DEVELOPING MANAGEMENT SKILLS EIGHTH EDITION David A. Whetten BRIGHAM YOUNG UNIVERSITY Kim S. Cameron UNIVERSITY OF MICHIGAN PrenticeRead MoreManagement Course: Mba−10 General Management215330 Words   |  862 Pageseconomic, social, and political churning, how will these driving factors be influenced by the brutally competitive global economy in which organizations do not have any particular geographic identity or travel under any particular national passport? What will be the effect of the rapid gyrations in markets that emphasize the difficulties that accounting practices face in determining true performance costs and that forecasting programs confront in establishing the economic determinants of corporate

Wednesday, May 6, 2020

Riding the Winds of Change Free Essays

If I had to choose two of the best traits that I have as a person, it would be my determination and my ability to cope quite well with transition. There had been a point in my life that these traits had been put to the test. It happened when I transferred from a liberal studies program in Florence, Italy into a communications program in New York City. We will write a custom essay sample on Riding the Winds of Change or any similar topic only for you Order Now When I made this shift, I really felt the pressure of struggling to be independent. Living life when you have no one to depend on but yourself is hard to imagine. It is even harder to do. Nonetheless, it is only one of the many challenges I had to deal with as it is but a part of the greater demands of growing up and learning life’s lessons. All things considered, I had to say that I certainly felt more like an individual than I ever did when I was in Florence. For this, I would always take pride in going through that change in my life and successfully overcoming the obstacles which came my way. I somehow see myself in the character of Frederick Tubb. Otherwise known as Bootie, he is one of the characters in Claire Messud’s novel entitled The Emperor’s Children (Messud 160). He is the nephew of Murray Thwaite. He was an idealistic college dropout who was resolved leave a mark of his own. He came to New York City to do just this. He was bound to significantly change the lives of the characters in the story in a way that no one ever though would be possible. He was able to shatter the foundations of those who seemed to have carefully secured their positions to be on top of the world. The moment the worlds of the most successful people have collapsed, they were left with nothing but the wreckage of the material heaven they have traveled great lengths to build. The only thing that was left to do work on their individual self-redemption and brave the challenges ahead armed with an enlightened heart and soul as a result of knowing what really matters in life. Whenever life’s circumstances seem to pull all your defenses down, it is but natural to feel devastated. When you have defied seemingly impossible odds just to prove your self to the rest of the world, it is heartbreaking to one day wake up and learn that all of your hopes and dreams for the future have already crumbled. Just when you thought that tomorrow will bring bountiful blessings, sometimes it presents the worst events you can not even dare to imagine. When enjoy all the comforts in life that the average individual can only hope for, there is no guarantee that your life will never take a drastic turn for the worst. Times are there when success is within reach today but it is some thing which is next to impossible the following day. But life is really hard even for those who are more fortunate than the others. Come to think of it, how do we really measure success? Does it only translate to material wealth? Personally, I do believe that it does have to be so. The real essence of success for me goes beyond the comforts of life that money can buy. Success can also be measured by how far one has tested his or her limits. When one has gathered enough strength to leave his or her comfort zone and start all over again giving another shot at life, the positive outcome of such an endeavor would spell success. I may not own riches to the point that my neighbors would envy the life that I live but I had to say that I have tasted the sweetness of success in the span of my existence. My claims to fame my fail in comparison to certain people but I know what it feels like to be on top of the world. The moment I made one of the greatest transitions I ever did in my life, I must admit that I had my own share of fears and uncertainties of what lies ahead. However, my determination and ability to manage changes saw me through. Indeed, it was one of the most successful endeavors I have ever embarked on my life’s journey. How to cite Riding the Winds of Change, Papers